Prevacid®24HR is available over-the-counter...

Pill imprint TAP PREVACID 15 has been identified as Prevacid 15 mg.

1 PREVACID 15-mg capsules only.

GoodSense Acid Reducer, Lansoprazole Delayed Release Capsules, 15 mg, 42 Count

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  • PREVACID is indicated for the treatment of NSAID-associated gastric ulcer in patients who continue NSAID use. Controlled studies did not extend beyond 8 weeks .

    In one large U.S., multicenter, double-blind, placebo- and misoprostol-controlled (misoprostol blinded only to the endoscopist) study in patients who required chronic use of an NSAID and who had a history of an endoscopically documented gastric ulcer, the proportion of patients remaining free from gastric ulcer at 4, 8, and 12 weeks was significantly higher with 15 or 30 mg of PREVACID than placebo. A total of 537 patients were enrolled in the study, and 535 patients were treated. Patients ranged in age from 23 to 89 years (median age 60 years), with 65% female patients and 35% male patients. Race was distributed as follows: 90% Caucasian, 6% Black, 4% other. The 30 mg dose of PREVACID demonstrated no additional benefit in risk reduction of the NSAID-associated gastric ulcer than the 15 mg dose ()

  • PREVACID in combination with amoxicillin as dual therapy is indicated for the treatment of patients with infection and duodenal ulcer disease (active or one-year history of a duodenal ulcer) (see the clarithromycin package insert, MICROBIOLOGY section). Eradication of has been shown to reduce the risk of duodenal ulcer recurrence .

    PREVACID is indicated for reducing the risk of NSAID-associated gastric ulcers in patients with a history of a documented gastric ulcer who require the use of an NSAID. Controlled studies did not extend beyond 12 weeks .

    Table 18: Reflux Esophagitis Healing Rates in Patients Poorly Responsive to Histamine H2-Receptor Antagonist Therapy
    Week PREVACID
    30 mg daily
    (N=100)
    Ranitidine
    150 mg twice daily
    (N=51)
    *
    (p≤0.001) versus ranitidine.

    4

    74.7%*

    42.6%

    8

    83.7%*

    32.0%

  • Table 17: Erosive Esophagitis Healing Rates

    Week
    PREVACID
    30 mg daily
    (N=115)
    Ranitidine
    150 mg twice daily
    (N=127)
    *
    (p≤0.001) versus ranitidine.

    2

    66.7%*

    38.7%

    4

    82.5%*

    52.0%

    6

    93.0%*

    67.8%

    8

    92.1%*

    69.9%

    In two U.S. and Canadian multicenter, double-blind, active-controlled studies in patients with endoscopically confirmed NSAID-associated gastric ulcer who continued their NSAID use, the percentage of patients healed after 8 weeks was statistically significantly higher with 30 mg of PREVACID than with the active control. A total of 711 patients were enrolled in the study, and 701 patients were treated. Patients ranged in age from 18 to 88 years (median age 59 years), with 67% female patients and 33% male patients. Race was distributed as follows: 87% Caucasian, 8% Black, 5% Other. There was no statistically significant difference between PREVACID 30 mg daily and the active control on symptom relief (i.e., abdominal pain) ()

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Over 4,000 women were treated with PREVACID. Ulcer healing rates in females were similar to those in males. The incidence rates of adverse reactions in females were similar to those seen in males